"Assessing Arterial Compliance: Utilizing a Surrogate Arm Bench Top Mod" by Krystal Cardenas

Date of Award

3-2025

Degree Name

MS in Biomedical Engineering

Department/Program

Biomedical Engineering

College

College of Engineering

Advisor

Michael Whitt

Advisor Department

Biomedical Engineering

Advisor College

College of Engineering

Abstract

A study was conducted to evaluate the compliance of artificial artery systems utilizing an adaptation of the Yong-Geddes Surrogate Arm model, composed of a blood pressure cuff, artificial artery, pressure transducers, and flow to replicate physiological conditions to validate oscillometric non-invasive blood pressure measurement methods. The experiment phases included tube, blood pressure cuff, and the surrogate arm compliance tests both in static and dynamic conditions. Tube compliance tests showed that larger diameters resulted in increased compliance, with Sample 1 (smaller inner diameter, ID) resulting in an average compliance of 0.0912 mL/mmHg, and Sample 2 (bigger ID) resulting in 0.1597 mL/mmHg. Arterial compliance curves were fit to the data of Samples 1 and 2 with correlations of R2 = 96.56% and R2 = 98.55% respectively. Cuff compliance testing yielded an average compliance of 0.8991 cm2/mmHg, with a second-order inverse polynomial model achieving a strong fit (R2 = 85.02%). Static surrogate arm compliance tests revealed variability, with average compliance values of 0.1102 and 0.1862 for Samples 1 and 2, respectively with errors of 15.99–20.88% compared to tube compliance, highlighting the need for refinements in system design. Overall, the experiments demonstrated the model’s potential for compliance measurement, but identified variability and error, requiring further refinement. These findings provide a foundation for advancing surrogate arm systems and new techniques for validating noninvasive blood pressure systems models.

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