Recommended Citation
Published in United States Patent Number: 6,867,311 B2, March 15, 2005, pages 1-18.
NOTE: At the time of publication, the author Hasan Palandoken was not yet affiliated with Cal Poly.
Abstract
The present invention provides compounds and methods that can be used to convert the intermediate halomethyl ketones (HMKs), e.g., chloromethyl ketones, to the corresponding S,S- and R,S-diastereomers. More particularly, the present invention provides: (1) reduction methods; (2) inversion methods; and (3) methods involving the epoxidation of alkenes. Using the various methods of the present invention, the R,S-epoxide and the intermediary compounds can be prepared reliably, in high yields and in high purity.
Disciplines
Biochemistry | Chemistry
Number of Pages
17
Publisher statement
United States Patent Number: 6,867,311 B2, Mar. 15, 2005. Also available from the United States Patent and Trademark Office. Website: http://www.uspto.gov.
Included in
URL: https://digitalcommons.calpoly.edu/chem_fac/12