College - Author 1

College of Engineering

Department - Author 1

Biomedical Engineering Department

Degree Name - Author 1

BS in Biomedical Engineering

College - Author 2

College of Engineering

Department - Author 2

Biomedical Engineering Department

Degree - Author 2

BS in Biomedical Engineering

College - Author 3

College of Engineering

Department - Author 3

Biomedical Engineering Department

Degree - Author 3

BS in Biomedical Engineering

Date

3-2020

Primary Advisor

Christopher Heylman, College of Engineering, Biomedical Engineering Department

Additional Advisors

Britta Berg-Johansen, College of Engineering, Biomedical Engineering Department

Abstract/Summary

This document comprises the steps taken by the senior project team to create a Proof-of-Concept Review for a Variable Pulsed Electric Field Ablation Catheter. First, the team did a significant amount of background research on related literature to better understand the current status of the project topic. After sufficient background information was obtained, project objectives and deliverables were finalized. Once customer requirements and the indications for use were completed, engineering specifications for the product and project were documented. All key customer requirements and engineering specs were related to the variable pulse functionality, maneuverability, as well as overall dimensioning of the final design. Before project development truly began, the project management timeline and budget were created to keep the project team accountable and on-schedule throughout the project term. The official design and development process began with generation of preliminary concepts that were analyzed via a morphology and Pugh Chart analysis. Once final design decisions were made, CAD and simulation development commenced and continued throughout the remainder of the project term. In addition to a final CAD model and proof-of-concept simulation, the project team also provided manufacturing recommendations for future groups who attempt to continue this project in the future. Overall, this proofof-concept document includes details about a pulsed electric field (PEF) ablation catheter that utilize electric waves to provide simultaneous delivery of variable electrical pulses to the heart tissue. Data and measurements taken from both a COMSOL simulation and SolidWorks model demonstrate that a complex PEF ablation catheter, such as the one presented in this document, is feasible in a clinical setting. Specifically, the catheter designed would be able to fit within human cardiovasculature while still having the ability to deliver selective variable pulses capable of ablation 2-4mm into surrounding heart tissue. The information provided in this proof-of-concept can be used by future groups to both manufacture an actual physical prototype as well as continue to augment the PEF COMSOL simulation presented.

Share

COinS