College - Author 1

College of Engineering

Department - Author 1

Biomedical Engineering Department

Degree Name - Author 1

BS in Biomedical Engineering

College - Author 2

College of Engineering

Department - Author 2

Biomedical Engineering Department

Degree - Author 2

BS in Biomedical Engineering

College - Author 3

College of Engineering

Department - Author 3

Biomedical Engineering Department

Degree - Author 3

BS in Biomedical Engineering

Date

6-2020

Primary Advisor

Michael D. Whitt, College of Engineering, Biomedical Engineering Department

Abstract/Summary

The septal closure device was designed to seal defects in the atrial septum. To fully seal an atrial defect, the device was designed to consist of two circular seals to cover the defect in both the right and left atria, attached with a central rod. The materials were chosen for compressibility (for ease of insertion), biocompatibility, and tissue ingrowth. A CAD model was drafted in SolidWorks. Key customer requirements include ease of implantation (specifications: adjustable sizing and clear directions for use), physician controlled (specifications: short implantation time and compatibility with current catheter/scope techniques), and a long lifetime (specifications: materials that will not excessively degrade over time and material will become ingrown in endothelium). Key data that demonstrates functionality is plastic deformation not exceeding 1 mm after 2E9 cycles, no adverse reactions with the native tissue, and becoming ingrown with the native tissue.

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