College - Author 1
College of Science and Mathematics
Department - Author 1
Biological Sciences Department
Degree Name - Author 1
BS in Biological Sciences
Date
2015
Primary Advisor
Chris Kitts
Abstract/Summary
The bacterial composition of the human intestines contributes to much more than just digestion. In the inflammatory, autoimmune conditions primary sclerosing cholangitis (PSC) and ulcerative colitis (UC), the microbiome may be, in some cases, a factor. To gain a better understanding of the composition and stability of the microbiome in a patient treated with vancomycin for PSC, terminal restriction fragment (TRF) analysis was performed on 13 controls and 1 patient, and 16s rRNA microbiome composition analysis was performed on 1 patient and 3 controls. Results showed similar levels of stability, with surprising differences in composition.
URL: https://digitalcommons.calpoly.edu/biosp/36