This paper explains the potential impact of artificial intelligence on the American workforce with particular attention given to the manufacturing, service, and white-collar sectors. First, the conventional wisdom on this advancing technology is presented and analyzed. Then, using qualitative methodology in the form of case study research, this paper explores alternative solutions that demonstrate the rise of AI and the present and encroaching changes on the American workforce. According to this research, the American workforce will experience incredible transformations that must be met head on. The potential political and social consequences of this massive job loss are revealed, and suggestions of necessary social change and political regulation are presented. While the potential impacts of Artificial Intelligence have been discussed by mainstream media, this paper offers an in-depth, scholarly look into who exactly will be affected and how much they will be impacted.