Published in Proceedings of the 23rd Canadian Medical and Biological Engineering Conference: Toronto, January 1, 1997, pages 168-169. Copyright © 1997 Canadian Medical and Biological Engineering Society. Posted with permission from CMBES.
NOTE: At the time of publication, the author Robert Szlavik was not yet affiliated with Cal Poly.
The electrical excitation threshold of a nerve axon is dependent upon the physical properties of the axon membrane as well as the axon diameter. Histological studies have confirmed that peripheral afferent muscle nerves have a characteristic distribution of axon diameters. We approximate a probability density function for this distribution that consists of the summation of several Gaussian functions. A transformation technique is then applied for the random generation of the nerve axon diameters from uniformly distributed random numbers. For the example presented, the resultant distribution of peripheral afferent muscle nerve axon diameters conforms approximately to the characteristic distribution that has been observed experimentally.
Biomedical Engineering and Bioengineering